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完整大鼠和利血平化大鼠海马电刺激诱发的湿狗样身体抖动

Wet-dog body shaking induced by electrical stimulation of hippocampus in the intact and reserpinized rat.

作者信息

Yamada K, Matsuki J, Furukawa T

出版信息

Res Commun Chem Pathol Pharmacol. 1983 Jan;39(1):29-37.

PMID:6844737
Abstract

Electrical stimulation of the hippocampus evoked body shaking in both control and reserpinized rats. The incidence of shaking induced by hippocampal stimulation was higher in reserpine-treated rats than in control rats. Stimulation of the amygdala, striatum and substantia nigra failed to elicit shaking. Body shaking induced by hippocampal stimulation was inhibited by phentolamine but not by methysergide, atropine and haloperidol. The results indicate that hippocampal stimulation elicits body shaking in which noradrenergic function may be involved.

摘要

对对照组和利血平处理的大鼠进行海马体电刺激均诱发身体颤抖。利血平处理的大鼠中海马体刺激诱发颤抖的发生率高于对照组大鼠。刺激杏仁核、纹状体和黑质未能引发颤抖。海马体刺激诱发的身体颤抖可被酚妥拉明抑制,但不能被麦角酰二乙胺、阿托品和氟哌啶醇抑制。结果表明,海马体刺激引发身体颤抖,其中可能涉及去甲肾上腺素能功能。

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