有机溶剂污染的工作环境对淋巴细胞酸性磷酸酶活性的影响。
The effect of working environment contaminated with organic solvents on the activity of acid phosphatase in lymphocytes.
作者信息
Moszczyński P
出版信息
Med Interne. 1983 Jan-Mar;21(1):37-42.
PMID:6844841
Abstract
In 108 workers occupationally exposed to organic solvents containing benzene, toluene and xylene, the activity of acid phosphatase (AP) was determined in the peripheral blood lymphocytes. A positive correlation was found between the number of lymphocytes exhibiting redistribution of AP from lysosomes into the cytoplasm and the exposure time to the solvents. The cytochemical estimation of the lymphocyte AP activity might practically be used as a screening test for the early detection of the toxic effects of exposure to the above solvents.
摘要
在108名职业性接触含有苯、甲苯和二甲苯的有机溶剂的工人中，测定了外周血淋巴细胞中的酸性磷酸酶（AP）活性。发现AP从溶酶体重新分布到细胞质中的淋巴细胞数量与接触溶剂的时间之间存在正相关。淋巴细胞AP活性的细胞化学评估实际上可作为早期检测上述溶剂暴露毒性作用的筛查试验。
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