Kessler H A, Trenholme G M, Vogelzang N J, Patterson R, Semel J D, Harris A A, Levin S
Scand J Infect Dis. 1983;15(1):7-10. doi: 10.3109/inf.1983.15.issue-1.02.
24 patients admitted to hospital between December 1, 1977 and March 3, 1978 with cultural or serological evidence of influenza A infection were retrospectively analyzed for evidence of elevated creatine phosphokinase (CPK) levels. 14 patients had elevated CPK levels not attributable to usual causes. Muscle biopsies from 2 patients showed focal necrosis and myopathic changes. Influenza A/Texas/1/77 was isolated from the biopsy specimen of 1 patient. Patients with elevated CPK levels tended to have greater per day hospital costs and more complications than patients with normal CPK levels. Elevated CPK levels are relatively common in hospitalized patients with influenza and may be due to influenza virus involvement of skeletal muscle.
对1977年12月1日至1978年3月3日期间因甲型流感感染的培养或血清学证据而入院的24例患者进行回顾性分析，以寻找肌酸磷酸激酶（CPK）水平升高的证据。14例患者的CPK水平升高并非由常见原因所致。2例患者的肌肉活检显示局灶性坏死和肌病改变。从1例患者的活检标本中分离出甲型流感病毒/得克萨斯/1/77。与CPK水平正常的患者相比，CPK水平升高的患者每天的住院费用往往更高，并发症也更多。CPK水平升高在流感住院患者中相对常见，可能是由于流感病毒累及骨骼肌所致。
