神经嵴细胞有助于正常的主动脉肺动脉分隔。
Neural crest cells contribute to normal aorticopulmonary septation.
作者信息
Kirby M L, Gale T F, Stewart D E
出版信息
Science. 1983 Jun 3;220(4601):1059-61. doi: 10.1126/science.6844926.
PMID:6844926
Abstract
By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum. Bilateral removal of this neural crest population prior to migration causes malformation of the aorticopulmonary septum resulting in common arterial outflow channels or transposition of the great vessels.
摘要
通过分析鹌鹑 - 小鸡嵌合体的心脏，发现枕部体节1至3水平的神经嵴细胞迁移至主动脉肺动脉隔区域。在迁移前双侧去除这群神经嵴细胞会导致主动脉肺动脉隔畸形，从而造成共同动脉流出道或大血管转位。
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