Maliuk V I
Ukr Biokhim Zh (1978). 1983 Mar-Apr;55(2):216-7.
The paper deals with dynamics of tricarboxylic cycle metabolites in the liver after subcutaneous injection of succinate in a dose of 100 mg/kg to guinea pigs. Before the preparation administration the highest level was marked for succinate, malate and citrate. 3 h after the administration the succinate content increased by 57% and 6 h later it returns to the initial level. No essential changes were observed in the content of other tricarboxylic acid cycle metabolites.
该论文研究了以100毫克/千克的剂量给豚鼠皮下注射琥珀酸后，其肝脏中三羧酸循环代谢物的动态变化。在给予制剂前，琥珀酸、苹果酸和柠檬酸的水平最高。给药后3小时，琥珀酸含量增加了57%，6小时后又恢复到初始水平。其他三羧酸循环代谢物的含量未观察到显著变化。
