Rudolf K, Martens E, Hofmann R, Rüting M
Zentralbl Gynakol. 1983;105(4):193-7.
Our experiences in the treatment of functional sterility in 482 patients with clomiphene are reported. The dosage of clomiphene was 100 mg per day for 5 days. If treatment was without success after 3 cycles dosage was changed to 150 mg per day for 7 days. The ovulation induction rate detected by basal body temperature was 74.5%. Conceptions were obtained in 35.7%. Pregnancy was terminated by spontaneous abortion in 18.8%. In high weight patients there was the best success rate with clomiphene treatment.
本文报告了我们使用克罗米芬治疗482例功能性不孕患者的经验。克罗米芬的剂量为每日100毫克,共5天。如果3个周期治疗无效,则将剂量改为每日150毫克,共7天。通过基础体温检测的排卵诱导率为74.5%。受孕率为35.7%。18.8%的妊娠因自然流产而终止。在体重较大的患者中,克罗米芬治疗的成功率最高。