Cieciura L, Ruszczak Z, Wronka A, Krajewski J, Bartel H, Dec W
Zentralbl Gynakol. 1983;105(4):220-8.
The structure of normal and toxemic pregnancy (EPH-gestosis) placenta was analysed by goniometric observation. Hitherto the most characteristic symptom of gestotic placenta demonstrable by measurements appeared to be thickening of the placental basallayer consisting of the basal membranes of the capillary endothelium and syncytiotrophoblast. Observations were now made on 20 normal placentas and on 20 ones with full-clinical gestotic symptoms. Specimens prepared by conventional methods were examined with a Philips EM 300 electron microscope, equipped with a goniometer stage. Measurements of the placental basal layer in three goniometer positions: 0 degrees, + 45 degrees, - 45 degrees, were made from negatives of electron micrographs with a final magnification 135,200 x. Data were analysed statistically using Wilcoxon's test. We also used the planimetric-statistic method of Casley-Smith and Davy. We found the thickness of the gestotic placental basal layer to be significantly less than in a normal one. Ultrastructural markers of transport through the feto-maternal blood barrier were more evident that in normals. We suppose the increased placental transport and decreased thickness of the placental basal layer could be compensatory reactions to the pathological lesions of gestotic pregnancy.
通过测角观察分析了正常妊娠和中毒性妊娠（妊娠高血压综合征）胎盘的结构。迄今为止，通过测量可证实的妊娠中毒性胎盘最典型的症状似乎是由毛细血管内皮和合体滋养层的基底膜组成的胎盘基底层增厚。现在对20个正常胎盘和20个具有完全临床妊娠中毒症状的胎盘进行了观察。用配备测角台的飞利浦EM 300电子显微镜检查常规方法制备的标本。从最终放大倍数为135,200倍的电子显微镜照片负片上，在三个测角位置（0度、+45度、-45度）测量胎盘基底层。使用威尔科克森检验对数据进行统计分析。我们还使用了卡斯利-史密斯和戴维的平面统计方法。我们发现妊娠中毒性胎盘基底层的厚度明显小于正常胎盘。通过母胎血屏障的转运的超微结构标记比正常情况下更明显。我们推测胎盘转运增加和胎盘基底层厚度减小可能是对妊娠中毒性妊娠病理损伤的代偿反应。
