Vara-Thorbeck R, Maza-Inza J
Surg Gynecol Obstet. 1978 Sep;147(3):391-6.
A study was done on the action of splenohepatoplasty upon intrahepatic and prehepatic portal hypertension. Portal hypertension was induced Wistar rats following the establishment of cirrhotic conditions. Hepatic cirrhosis was obtained in these rats by an oral, daily dose of tioacetamide during a four and five month period. Prehepatic hypertension was produced in dogs by the installation of a rubber cylinder, completely covered by cellophane paper, around the trunk of the vena porta. This procedure brought about a progressive compression of the vena porta. The application of splenoheptoplasty is a highly valuable treatment for portal hypertension as a derivative system and for intrahepatic portal hypertension as a derivative regenerative system.
一项关于脾肝成形术对肝内和肝前门静脉高压作用的研究。在Wistar大鼠建立肝硬化状态后诱导门静脉高压。通过在4至5个月期间每日口服硫代乙酰胺使这些大鼠患上肝硬化。通过在门静脉主干周围安装一个完全用玻璃纸覆盖的橡胶圆柱体在犬身上制造肝前门高压。该操作导致门静脉逐渐受压。脾肝成形术作为一种分流系统对于门静脉高压以及作为一种分流再生系统对于肝内门静脉高压而言是一种非常有价值的治疗方法。
