Liu Z
First Clinical College, Norman Bethune University of Medical Sciences, Changchun.
Zhonghua Wai Ke Za Zhi. 1990 Jun;28(6):374-7, 383.
In this study, the side-to-side (MCS-SS) and end-to-side (MCS-ES) mesocaval shunt were performed in two groups of thioacetamide (TAA)-induced cirrhosis of rats. The anastomotic stoma was made equal to the calibre of mesenteric veins. It was found that the portal vein pressure after MCS-SS was lower than that after MCS-ES owing to the more effective drainage of both extra- and intrahepatic portal blood flow. It was also found that with MCS-SS, some inflow from the superior mesenteric vein was reserved to irrigate the liver and the content of insulin in the portal vein was not affected. The authors came to the conclusion that MCS-SS was superior to MCS-ES for less likely causing post-shunt encephalopathy and the deterioration of hepatic function.
在本研究中，对两组硫代乙酰胺（TAA）诱导的大鼠肝硬化模型分别实施了侧侧门腔分流术（MCS-SS）和端侧门腔分流术（MCS-ES）。吻合口造得与肠系膜静脉管径相等。结果发现，由于肝内外门静脉血流的引流更有效，MCS-SS术后的门静脉压力低于MCS-ES术后。还发现，行MCS-SS时，肠系膜上静脉的一些血流得以保留以灌注肝脏，门静脉中的胰岛素含量未受影响。作者得出结论，MCS-SS在降低分流术后肝性脑病及肝功能恶化的发生率方面优于MCS-ES。
