Halverson J D, Gentry K, Wise L, Ballinger W F
Surgery. 1978 Aug;84(2):241-9.
One hundred and one patients underwent jejunoileal bypass after careful preoperative evaluation. These patients were re-evaluated after operation on a frequent basis, and 23% have required restoration of intestinal continuity (reanastomosis) by a mean postoperative time of 44 months. The most frequent reasons for reanastomosis were liver dysfunction (5% of the entire series), severe malnutrition or weakness (5%), and late electrolyte imbalance (4%). Two patients did not survive reanastomosis, both having liver failure. Of the patients who did survive, weight gain (approaching prebypass weight) and improvement in liver function tests, electrolyte balance, serum vitamin levels, and diarrhea have been the rule. Of the entire series of 101 patients who underwent bypass, 58% either had life-threatening complications, had to be reanastomosed, or died. These morbidity and mortality rates raise the important question of whether jejunoileal bypass is an appropriate procedure for the treatment of morbid obesity.
101例患者在经过仔细的术前评估后接受了空肠回肠分流术。术后对这些患者进行了频繁的重新评估,23%的患者在术后平均44个月时需要恢复肠道连续性(重新吻合)。重新吻合最常见的原因是肝功能障碍(占整个系列的5%)、严重营养不良或虚弱(5%)以及晚期电解质失衡(4%)。两名患者在重新吻合术后未能存活,均死于肝功能衰竭。存活的患者体重增加(接近分流术前体重),肝功能检查、电解质平衡、血清维生素水平和腹泻情况均有所改善,这是普遍规律。在接受分流术的101例患者中,58%的患者出现了危及生命的并发症、需要重新吻合或死亡。这些发病率和死亡率引发了一个重要问题,即空肠回肠分流术是否是治疗病态肥胖的合适手术。