Gangadharam P R, Edwards C K, Murthy P S, Pratt P F
Am Rev Respir Dis. 1983 May;127(5):648-9. doi: 10.1164/arrd.1983.127.5.648.
The development of an acute infection model of Mycobacterium intracellulare disease in Beige mice (C57B1/6J-bgJ/bgJ) was investigated. Intravenous injection of 1 x 10(7) viable colony-forming units of M. intracellulare strain 571-8 produced a 1,000-fold increase in the number of mycobacteria recovered from the lungs and spleens after 28 days of infection. More importantly, 40% of the beige mice died from this infection, as was determined from histopathologic sections and bacterial culturing.
研究了米色小鼠（C57B1/6J-bgJ/bgJ）细胞内分枝杆菌病急性感染模型的建立。静脉注射1×10⁷个细胞内分枝杆菌菌株571-8的活菌落形成单位，感染28天后，从肺和脾中回收的分枝杆菌数量增加了1000倍。更重要的是，通过组织病理学切片和细菌培养确定，40%的米色小鼠死于这种感染。
