Bijster P, Vader H L, Vink C L
Ann Clin Biochem. 1983 Mar;20 Pt 2:116-20. doi: 10.1177/000456328302000211.
We have shown that the sodium concentration in whole blood measured by direct potentiometry is higher than in plasma. The 'erythrocyte-effect', already described by Siggaard Andersen, is most pronounced for instruments equipped with a reference electrode with an open static liquid junction and is thus a general phenomenon. Instruments with a modified liquid junction show less interference. The same phenomenon appears for the determination of the potassium concentration, although the difference between whole blood and plasma, when measured with instruments equipped with a modified liquid junction, can be neglected in practice.
我们已经表明，通过直接电位法测量的全血中钠浓度高于血浆中的钠浓度。西格加德·安德森已经描述过的“红细胞效应”，对于配备有开放式静态液体接界的参比电极的仪器最为明显，因此是一种普遍现象。具有改良液体接界的仪器显示出较少的干扰。在用配备有改良液体接界的仪器进行测量时，全血和血浆之间的差异在实际中可以忽略不计，但在测定钾浓度时也会出现同样的现象。
