Ladenson J H
Clin Chem. 1977 Oct;23(10):1912-6.
I compared results for sodium and potassium in whole blood and plasma as measured with a newly available potentiometric analyzer, the "Orion SS-30". No significant difference was found for either sodium or potassium in 207 such comparisons. With use of the flowing, high mixing-velocity liquid junction of the Orion SS-30, the residual liquid junction potential due to blood cells was found to be less than 0.1 mV and to be independent of the hematocrit. This is in contrast to the hematocrit-dependent residual liquid junction potential of approximately 0.6 mV noted by others at normal hematocrit values with the open capillary liquid junctions now commonly used in pH instruments. I also found that the potassium concentration can increase significantly during the mixing of whole blood, and such samples should be mixed gently, if at all. Evidently sodium and potassium can be accutately and easily measured directly in heparinized blood.
我比较了使用新的电位分析仪“奥立龙SS - 30”测量全血和血浆中钠和钾的结果。在207次此类比较中，钠和钾均未发现显著差异。使用奥立龙SS - 30的流动、高混合速度液体接界时，发现血细胞引起的残余液体接界电位小于0.1 mV，且与血细胞比容无关。这与其他人在正常血细胞比容值下使用pH仪器中常用的开放毛细管液体接界时所指出的约0.6 mV的血细胞比容依赖性残余液体接界电位形成对比。我还发现，全血混合过程中钾浓度会显著增加，因此此类样本如果需要混合，应轻轻混合。显然，钠和钾可以在肝素化血液中直接准确且轻松地测量。
