Helling T S, Wood W G
Arch Surg. 1983 Jun;118(6):765-8. doi: 10.1001/archsurg.1983.01390060081018.
An elderly woman with documented pernicious anemia was found to have diffuse involvement of the gastric mucosa, with carcinoid tumors. In reviewing the English-language literature we found 14 additional patients who had atrophic gastritis, pernicious anemia, and gastric carcinoids. This finding suggests that there is a more than coincidental association, although firm clinical and experimental proof is lacking. Nevertheless, appearance of gastrointestinal tract symptoms in patients with pernicious anemia should alert the clinician to the possible presence of gastric carcinoid tumors.
一名患有确诊恶性贫血的老年女性被发现胃黏膜弥漫性受累,并伴有类癌肿瘤。在查阅英文文献时,我们又发现了14例患有萎缩性胃炎、恶性贫血和胃类癌的患者。这一发现表明存在一种并非偶然的关联,尽管缺乏确凿的临床和实验证据。然而,恶性贫血患者出现胃肠道症状应提醒临床医生注意可能存在胃类癌肿瘤。