Egorov V P, Naumov V N
Arkh Patol. 1983;45(2):78-82.
This paper is the first publication of malignant giant cell tumors (MGCT) of the uterus in the Soviet literature. From the analysis of 2 own observations and 2 cases reported in the literature the authors describe the typical macroscopical appearance and histological picture of MGCT of the uterus similar to those of analogous tumors of soft tissues and some organs. The clinical behavior of these tumors depends not so much on histological variant as on the pattern of their growth and degree of differentiation of the tumor tissue. Despite ultrastructural features suggesting their fibrohistiocytic origin of MGCT, their true histogenesis remains obscure.
本文是苏联文献中关于子宫恶性巨细胞瘤(MGCT)的首次发表。通过对作者自身的2例观察病例以及文献报道的2例病例进行分析,作者描述了子宫MGCT典型的宏观外观和组织学表现,这些表现与软组织及一些器官的类似肿瘤相似。这些肿瘤的临床行为与其组织学类型的关系不大,而更多地取决于其生长方式和肿瘤组织的分化程度。尽管超微结构特征提示MGCT起源于纤维组织细胞,但它们真正的组织发生仍然不明。