Chesson A L, Kasarskis E J, Small V W
Arch Neurol. 1983 May;40(5):315-7. doi: 10.1001/archneur.1983.04050050083013.
Serial serum creatine kinase (CK) level determinations were performed on selected patients for six days following tonic-clonic or focal motor seizures in a prospective study. The time course and magnitude of serum CK elevation was correlated with seizure CK level was observed in all patients. Isoenzyme determinations revealed that CK was derived from skeletal muscle. Our data demonstrate that profound elevations of serum CK level may occur postictally and appear to be related to the intensity of muscular activity. patients with seizures associated with alcohol abuse had the greatest postictal serum CK level increases.
在一项前瞻性研究中，对部分患者在强直阵挛性发作或局灶性运动性发作后的六天内进行了连续血清肌酸激酶（CK）水平测定。在所有患者中均观察到血清CK升高的时间过程和幅度与发作时的CK水平相关。同工酶测定显示CK来源于骨骼肌。我们的数据表明，血清CK水平在发作后可能会显著升高，并且似乎与肌肉活动的强度有关。与酒精滥用相关的癫痫发作患者发作后的血清CK水平升高幅度最大。
