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[雌性基因型对t单倍型向T/t6复合雄性小鼠子代传递频率的修饰作用]

[Modifying effect of the female genotype on the frequency of t-haplotype transmission to the progeny of T/t6 compound male mice].

作者信息

Demin Iu S, Safronova L D, Lapkin Iu A

出版信息

Tsitol Genet. 1978 Jan-Feb;12(1):36-9.

PMID:684810
Abstract

Female genotype effects on the transmission of t-haplotypes from heterozygous males to offspring has been established. The CBA females transmitted T-gene to 29 per cent, C57BL/6 females to 47 per cent, and F1 hybrid females to 39 per cent of their offspring. The differences in the transmission rate are supposed to depend on female genotype and to be determined by selective ageing of T-carrying sperms in female genital tract when compared to t6-carrying sperms, because the interval between copulation and syngamy in C57BL/6 females is shorter than in CBA females. These data indicate the phenotypical differences between T- and t6-carrying sperms.

摘要

雌性基因型对t单倍型从杂合雄性传递给后代的影响已得到证实。CBA雌性将T基因传递给29%的后代,C57BL/6雌性传递给47%的后代,F1杂交雌性传递给39%的后代。传递率的差异被认为取决于雌性基因型,并且与携带t6的精子相比,是由雌性生殖道中携带T的精子的选择性衰老决定的,因为C57BL/6雌性中交配与受精之间的间隔比CBA雌性短。这些数据表明了携带T和t6的精子之间的表型差异。

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