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[敖德萨及其郊区乌克兰人的人类白细胞抗原]

[HLA antigens among Ukrainians in Odessa and its suburbs].

作者信息

Krivda G F

出版信息

Tsitol Genet. 1978 Jan-Feb;12(1):64-8.

PMID:684813
Abstract

389 Ukrainians of Odessa and its suburbs were typed in accordance with HLA system. HLA antigens distribution corresponded to Hardy-Weinberg's law. The antigens in the Ukrainians which occurred more frequently were A2, 3, Iw25, B12, 7 and Bw35. The most frequent haplotypes turned out to be A2, B12, A3, B7; Aw25, Bw16 and A1, B8. The highest gamete association wat noted for these haplotypes. The smallest genetic distance was found between the Odessa Ukrainian and Moscow Russian population, while the greatest distance was revealed between the Ukrainian and Japanese population.

摘要

对敖德萨及其郊区的389名乌克兰人进行了HLA系统分型。HLA抗原分布符合哈迪-温伯格定律。乌克兰人中出现频率较高的抗原是A2、3、Iw25、B12、7和Bw35。最常见的单倍型是A2、B12、A3、B7;Aw25、Bw16和A1、B8。这些单倍型的配子关联度最高。敖德萨乌克兰人与莫斯科俄罗斯人群之间的遗传距离最小,而乌克兰人与日本人群之间的遗传距离最大。

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