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[法国菲尼斯泰尔省人群中HLA抗原的分布(作者译)]

[Distribution of HLA antigens among the population of Finistère (France) (author's transl)].

作者信息

Saleun J P, Morin J F, Youinou P

出版信息

Nouv Rev Fr Hematol (1978). 1978;20(4):599-604.

PMID:752152
Abstract

We have studied by using HLA system, 200 people, without filiation but having the same geographic origine (Finistère). The results have been compared with those measured for Parisian and Basque population. A significantly decrease of antigen A29, B18 and BW16 frequency have been observed in the population from Finistere. But, antigen B8 and B27 seems to be more frequent than in population from Paris. A linkage desequilibrium is described for A1-B8 and A3-B7 haplotypes as in population from Paris, but the desequilibrium for A11-B5 seens to be characteristic of population from Finistere.

摘要

我们使用HLA系统对200名无血缘关系但有相同地理起源(菲尼斯泰尔省)的人进行了研究。研究结果与针对巴黎人和巴斯克人群体所测得的结果进行了比较。在来自菲尼斯泰尔省的人群中,观察到抗原A29、B18和BW16的频率显著降低。但是,抗原B8和B27在该人群中似乎比在巴黎人群中更常见。正如在巴黎人群中一样,在来自菲尼斯泰尔省的人群中也描述了A1 - B8和A3 - B7单倍型的连锁不平衡,但A11 - B5的不平衡似乎是菲尼斯泰尔省人群的特征。

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