庆大霉素增强镁诱导的神经肌肉无力。
Potentiation of magnesium-induced neuromuscular weakness by gentamicin.
作者信息
L'Hommedieu C S, Huber P A, Rasch D K
出版信息
Crit Care Med. 1983 Jan;11(1):55-6. doi: 10.1097/00003246-198301000-00015.
Abstract
A term neonate with hypermagnesemia secondary to maternal administration of MgSO4 for pre-eclampsia had a respiratory arrest after receiving gentamicin im. The neuromuscular tracings and sequential physician exams done before and after administering gentamicin suggest aminoglycosides may potentiate a magnesium-induced impairment of neuromuscular transmission and cause muscular weakness in neonates.
摘要
一名足月儿因母亲为治疗先兆子痫而使用硫酸镁导致高镁血症，在肌内注射庆大霉素后发生呼吸骤停。在注射庆大霉素前后进行的神经肌肉描记和连续体格检查表明，氨基糖苷类药物可能会增强镁诱导的神经肌肉传递损害，并导致新生儿肌肉无力。
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