Currier R D, Routh A, Hickman B T, Douglas M A
Radiology. 1983 Jan;146(1):199-201. doi: 10.1148/radiology.146.1.6849045.
Twenty-eight patients with progressive myasthenia gravis without thymoma received treatment of 3000 rads (30 Gy) to the anterior mediastinum, and a followup was conducted for five to 18 years. Twenty-four patients had generalized myasthenia, and four had ocular myasthenia gravis. Twenty patients with generalized myasthenia survived the several month post-treatment period and improved, but four died during that period. The improvement lasted a median of 1.5 years, and older patients had longer remissions than younger patients. The four patients who had ocular myasthenia did not change after treatment. Mediastinal irradiation produces a temporary remission in generalized myasthenia.
28例无胸腺瘤的进行性重症肌无力患者接受了前纵隔3000拉德（30戈瑞）的放疗，并进行了5至18年的随访。24例患者为全身型重症肌无力，4例为眼肌型重症肌无力。20例全身型重症肌无力患者在治疗后的几个月内存活且病情改善，但4例在此期间死亡。改善持续的中位时间为1.5年，老年患者的缓解期比年轻患者更长。4例眼肌型重症肌无力患者治疗后无变化。纵隔放疗可使全身型重症肌无力暂时缓解。
