Smith A J
S Afr Med J. 1983 Jan 8;63(2):45-7.
Phosphatidyl-glycerol (PG) and the lecithin/sphingomyelin (L/S) ratio were determined on amniotic fluid from 140 patients to evaluate the role of PG estimation as a functional fetal lung maturity test. PG was absent without associated respiratory distress syndrome (RDS) in 17 cases (12%) and present in 123, 3 of the infants born to these patients developed slight hyaline membrane disease. There were no neonatal deaths. When both PG and the L/S ratio were determined the accuracy of prediction of the RDS improved from 87% to 93%. PG determination should not be used as a substitute for the L/S ratio, but should be used in conjunction with it in high-risk situations.
对140例患者的羊水进行磷脂酰甘油（PG）和卵磷脂/鞘磷脂（L/S）比值测定，以评估PG测定作为功能性胎儿肺成熟度检测的作用。17例（12%）患者羊水无PG且无相关呼吸窘迫综合征（RDS），123例患者羊水有PG，这些患者所生婴儿中有3例发生轻度透明膜病。无新生儿死亡。当同时测定PG和L/S比值时，RDS预测的准确性从87%提高到93%。PG测定不应替代L/S比值，而应在高危情况下与L/S比值联合使用。
