Delbridge L, Appleberg M, Reeve T S
Surgery. 1983 Jan;93(1 Pt 1):78-82.
A prospective study was undertaken of 80 diabetic patients over the age of 50 years, with the aim of determining which factors were important in the development of foot lesions. It was found that factors associated with diabetic management, including HbAlc levels and frequency of previous admissions to hospital for diabetic control, appeared to play little part in the development of foot lesions. However, both vascular impairment and cigarette smoking were significantly associated with an increased incidence of lesions, while neuropathy was found to occur commonly in control subjects as well as patients with foot lesions. There was also a significant relationship between the level of patient understanding as measured by a questionnaire and the development of foot lesions. The importance of the education of both patients and doctors concerning the significance of diabetic foot lesions is emphasized.
对80名年龄超过50岁的糖尿病患者进行了一项前瞻性研究,目的是确定哪些因素在足部病变的发生中起重要作用。结果发现,与糖尿病管理相关的因素,包括糖化血红蛋白(HbAlc)水平和既往因糖尿病控制而住院的频率,似乎在足部病变的发生中作用不大。然而,血管损伤和吸烟均与病变发生率增加显著相关,而神经病变在对照受试者以及有足部病变的患者中均普遍存在。通过问卷调查衡量的患者理解水平与足部病变的发生之间也存在显著关系。强调了对患者和医生进行关于糖尿病足病变重要性教育的重要性。