Sanders D R, Spigelman A, Kraff C, Lagouros P, Goldstick B, Peyman G A
Arch Ophthalmol. 1983 Jan;101(1):131-3. doi: 10.1001/archopht.1983.01040010133026.
Breakdown and reestablishment of the blood-aqueous barrier (BAB) following experimental surgical trauma was evaluated by anterior segment slitlamp fluorophotometry. Substantially more fluorescein leakage was caused by 6-mm limbal incisions for at least the first four postoperative days than was produced by 3-mm incisions. Following 3-mm corneal incisions, leakage of fluorescein closely paralleled that of fluorescein-labeled dextran 70 (molecular weight, 70,000) for the first three postoperative days. On the fourth postoperative day, the BAB appeared reestablished to fluorescein-labeled dextran 70 but was still abnormally permeable to fluorescein. Thus, it appears that although fluorescein is the most sensitive technique of demonstrating breakdown of BAB, it may not always be an indicator of large-molecule permeability.
通过眼前节裂隙灯荧光光度法评估实验性手术创伤后血-房水屏障（BAB）的破坏和重建情况。至少在术后的头四天，6毫米角膜缘切口引起的荧光素渗漏明显多于3毫米切口。在3毫米角膜切口后，术后头三天荧光素的渗漏与荧光素标记的右旋糖酐70（分子量70,000）的渗漏密切平行。在术后第四天，BAB对荧光素标记的右旋糖酐70似乎已重建，但对荧光素仍具有异常通透性。因此，尽管荧光素是显示BAB破坏的最敏感技术，但它可能并不总是大分子通透性的指标。
