尽管存在废用或去神经支配情况，大鼠神经肌肉接头处乙酰胆碱受体仍会出现成熟性增加。
A maturational increase in rat neuromuscular junctional acetylcholine receptors despite disuse or denervation.
作者信息
Labovitz S S, Robbins N
出版信息
Brain Res. 1983 Apr 25;266(1):155-8. doi: 10.1016/0006-8993(83)91320-3.
PMID:6850343
Abstract
Junctional acetylcholine receptors (AChR) of rat skeletal muscles were microassayed 4-7 days after denervation or total disuse. The normal growth-related increase in AChR number occurred despite denervation or muscle atrophy, but in disused muscles, this increase was less. Thus, at least for short periods, the developmental addition of junctional AChR is independent of muscle fiber size or innervation and partly independent of usage.
摘要
在去神经支配或完全废用4 - 7天后，对大鼠骨骼肌的接头型乙酰胆碱受体（AChR）进行了微量测定。尽管存在去神经支配或肌肉萎缩，但AChR数量仍出现了与正常生长相关的增加，不过在废用的肌肉中，这种增加较少。因此，至少在短期内，接头型AChR的发育性增加与肌纤维大小或神经支配无关，且部分与使用情况无关。
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