Abrahamsohn P, Lundkvist O, Nilsson O
Cell Tissue Res. 1983;229(2):269-80. doi: 10.1007/BF00214975.
The ultrastructure of the blood vessels of the endometrium was analysed during implantation of the blastocyst in rats, at the time of appearance of the Pontamine Blue Reaction. Vessels from implantation sites and from interimplantation sites were compared. In vessels from implantation sites the endothelial cells showed fenestrations covered by diaphragms. In addition, small interruptions (gaps) between the endothelial cells were observed. These features were present in vessels larger than 5 micrometers in diameter and more than 100 micrometers away from the uterine epithelium, both in the mesometrial and antimesometrial wall of the endometrium. Vessels from interimplantation sites displayed neither fenestrations nor interruptions. The endothelial cells of the implantation sites displayed morphological signs of metabolic activation. These consisted of increased numbers of polyribosomes, well developed Golgi complexes and prominent nucleoli. The fenestrations and gaps in the vessel wall were interpreted as constituting the morphological basis for the increase in vascular permeability and the consequent edema which characterize the Pontamine Blue Reaction.
在大鼠胚泡着床期间,即出现滂胺蓝反应时,对子宫内膜血管的超微结构进行了分析。比较了着床部位和非着床部位的血管。着床部位的血管中,内皮细胞显示有被隔膜覆盖的窗孔。此外,还观察到内皮细胞之间有小的中断(间隙)。这些特征存在于直径大于5微米且距子宫上皮100多微米的血管中,在内膜的子宫系膜壁和反子宫系膜壁均如此。非着床部位的血管既没有窗孔也没有中断。着床部位的内皮细胞表现出代谢活化的形态学迹象。这些迹象包括多核糖体数量增加、高尔基体发达和核仁突出。血管壁上的窗孔和间隙被解释为构成血管通透性增加以及随之而来的水肿的形态学基础,而水肿是滂胺蓝反应的特征。