含铜7型宫内节育器（Cu-7）临床试验中盆腔炎的发病率：一项统计分析。

Incidence of pelvic inflammatory disease in clinical trials with Cu-7 (intrauterine copper contraceptive): a statistical analysis.

作者信息

O'Brien F B, Stewart W C, Sturtevant F M

出版信息

Contraception. 1983 Feb;27(2):111-22. doi: 10.1016/0010-7824(83)90082-3.

Abstract

Pelvic inflammatory disease (PID) was recorded for 365 of 10,760 women using the Cu-7 for up to 48 months during clinical investigations in the United States. This involved a total exposure of 242,169 woman-months, or some 20,000 woman-years. The overall incidence of PID was 18 cases/1000 woman-years. Incidence was inversely related to age and to duration of use. It was statistically significantly greater in parous subjects than in nulliparous, after stratifying for age. The estimated rates in this study do not differ markedly from those in most other prospective investigations.

摘要

在美国进行的临床研究中，10760名使用铜-7宫内节育器长达48个月的女性中有365例被记录患有盆腔炎（PID）。这涉及的总暴露量为242169妇女月，约合20000妇女年。PID的总体发病率为18例/1000妇女年。发病率与年龄和使用时间呈负相关。在按年龄分层后，经产妇的发病率在统计学上显著高于未产妇。本研究中的估计发病率与大多数其他前瞻性研究的发病率没有显著差异。