Präuer H W, Gullotta U, Becker K, Mack D
Dtsch Med Wochenschr. 1983 Jun 3;108(22):850-5. doi: 10.1055/s-2008-1069654.
Plasma cell granuloma of the lung is a rare, benign focal lesion of nonspecific inflammatory genesis with few symptoms and often discovered by chance during mass-radiography. Radiologically it is characterized by a usually well-circumscribed solitary round focus (70% of cases), as an infiltrate or as atelectasis if it grows endobronchially. The histological picture is polymorph with mature plasma cells, lymphocytes, vacuolized histiocytes, fibroblasts and other elements of the reticulo-endothelial system. It has been given many names, pseudotumour appearing in the older literature. In the differential diagnosis a peripheral lesion can be mistaken for benign tumour, specific granuloma or metastasis, the more central form for bronchial carcinoma. The condition was observed in six personal cases, operated on between 1967 and 1982.
肺浆细胞性肉芽肿是一种罕见的、非特异性炎症起源的良性局灶性病变,症状较少,常在集体X线检查时偶然发现。放射学上,其特征通常为边界清晰的孤立圆形病灶(70%的病例),若在内支气管生长则表现为浸润或肺不张。组织学表现多样,有成熟的浆细胞、淋巴细胞、空泡化组织细胞、成纤维细胞及网状内皮系统的其他成分。它有许多名称,在较早的文献中被称为假瘤。在鉴别诊断中,外周性病变可能被误诊为良性肿瘤、特异性肉芽肿或转移瘤,而更靠近中心的形态则可能被误诊为支气管癌。本文观察了1967年至1982年间手术治疗的6例个人病例。