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气溶胶电荷对大鼠体内二氧化钛颗粒沉积和清除的影响。

The effect of aerosol charge on the deposition and clearance of TiO2 particles in rats.

作者信息

Ferin J, Mercer T T, Leach L J

出版信息

Environ Res. 1983 Jun;31(1):148-51. doi: 10.1016/0013-9351(83)90071-3.

DOI:10.1016/0013-9351(83)90071-3
PMID:6851979
Abstract

A titanium dioxide aerosol when generated by a Wright dust feed will have a higher electrostatic charge by a factor of 5.5 than one which has been discharged by a bipolar ion field produced by a 7.5 mCi 85Kr source. The deposition of particles in the lung of rats was lower by approximately 21% when an aerosol discharger was used. Particle clearance from the lung alveoli was not affected by the use of the discharger.

摘要

由赖特粉尘进料器产生的二氧化钛气溶胶所带静电荷比由7.5毫居里85氪源产生的双极离子场消除电荷后的气溶胶高5.5倍。使用气溶胶放电装置时,大鼠肺部颗粒沉积量降低约21%。肺泡颗粒清除不受放电装置使用的影响。

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