Luwaert R J, Cosyns J, Rousseau M F, Brasseur L A, Detry J M, Brohet C R
Eur Heart J. 1983 Feb;4(2):103-9. doi: 10.1093/oxfordjournals.eurheartj.a061423.
Previous studies have demonstrated the existence of a strong positive correlation between the amplitude of QRS forces of the orthogonal electrocardiogram and the angiographically determined left ventricular ejection fraction. In a large group of patients evaluated for chest pain, we examined the relationship between the arithmetic summation of RX + RY + QZ (sigma R), the maximal and mean spatial QRS vectors and the ejection fraction (EF). In a total of 252 patients, there was a statistically significant correlation between sigma R and EF but a low correlation coefficient value (r:0.22, P less than 0.001). This relationship was essentially due to the group of patients with coronary artery disease and myocardial infarction (r:0.24, P less than 0.015) whereas there was no correlation in the group of normal subjects or in patients with coronary artery disease without myocardial infarction. In the group with myocardial infarction, a significant correlation between sigma R and EF existed only in patients with anterior myocardial infarction (r:0.41, P less than 0.025). In conclusion, both ejection fraction and amplitude of QRS forces decrease in coronary artery disease especially when an anterior myocardial infarction is present. However, despite the positive association between these angiographic and electrocardiographic indices, the low value of the correlation coefficient indicates that it is not possible to predict ejection fraction from the value of sigma R in individual patients.
既往研究已证实，正交心电图的QRS波力幅度与血管造影测定的左心室射血分数之间存在强正相关。在一大组因胸痛接受评估的患者中，我们研究了RX + RY + QZ（σR）的算术总和、最大和平均空间QRS向量与射血分数（EF）之间的关系。在总共252例患者中，σR与EF之间存在统计学显著相关性，但相关系数值较低（r：0.22，P＜0.001）。这种关系主要归因于冠心病和心肌梗死患者组（r：0.24，P＜0.015），而在正常受试者组或无心肌梗死的冠心病患者组中无相关性。在心肌梗死组中，σR与EF之间的显著相关性仅存在于前壁心肌梗死患者中（r：0.41，P＜0.025）。总之，在冠心病中，尤其是存在前壁心肌梗死时，射血分数和QRS波力幅度均降低。然而，尽管这些血管造影和心电图指标之间存在正相关，但相关系数值较低表明，无法根据个体患者的σR值预测射血分数。
