Minervini R, Carlino F, Fiorentini L
Eur Urol. 1983;9(2):80-3. doi: 10.1159/000474053.
The results obtained in a series of 233 subjects who underwent surgery for total cystectomy and ureterosygmoidostomy for carcinoma of the bladder are analyzed. The immediate and long-term results, the complications and length of survival, both in general and in relation to the stage of the neoplasia, have been considered. The surgical death rate was 7%. Survival, taking all cases into account, was 80% after 1 year, 55% after 3 years, 36% after 5 years and 8.3% after 10 years. Significant differences in survival were found among those patients with pathologic stage PIS-P1-P2 and those with P3-P4. From a survival of 64% after 5 years in the first group, we pass to 23% for P3 and 0% for P4. The precocious complications are anastomosis stenosis (1.8%), uro-fecal fistulae (1.8%) and urinary fistulae (1.4%). Late complications are anastomosis stenosis (13.6%), pyelonephritis with episodes of fever (19.3%), severe acidosis (1.8%) and kidney stones (1.8%).
对233例行膀胱全切术及输尿管乙状结肠吻合术治疗膀胱癌患者的结果进行了分析。考虑了近期和远期结果、并发症及生存时长，包括总体情况以及与肿瘤分期的关系。手术死亡率为7%。综合所有病例，1年后生存率为80%，3年后为55%，5年后为36%，10年后为8.3%。病理分期为PIS-P1-P2的患者与P3-P4的患者在生存率上存在显著差异。第一组患者5年后生存率为64%，而P3期患者降至23%，P4期患者为0%。早期并发症有吻合口狭窄（1.8%）、尿粪瘘（1.8%）和尿瘘（1.4%）。晚期并发症有吻合口狭窄（13.6%）、伴有发热发作的肾盂肾炎（19.3%）、严重酸中毒（1.8%）和肾结石（1.8%）。
