Wyler A R
Exp Neurol. 1983 Jun;80(3):697-707. doi: 10.1016/0014-4886(83)90319-9.
One hundred thirty-three pairs of precentral neurons were recorded simultaneously from four Macaca mulatta monkeys during participation in an operant conditioning paradigm that required one of the two units to be fired tonically within a 30- to 60-ms interspike interval (ISI) range. At the end of each 5-min behavioral period, a correlation between the two units' firing rate fluctuations was computed. These correlations were used as a measure of synchrony between units. For the majority of unit pairs, the unit for which reinforcement was contingent upon could be controlled independently from the activity of the simultaneously recorded unit. In 75% of experiments the synchrony between units decreased during the operant periods in comparison to the time-out periods. In only 5% of the experiments did unit pairs consistently exhibit increased synchrony during operant periods compared with time-out periods. If the monkey developed EEG signs of drowsiness during time-out periods, the synchrony between units became greater.
在四只恒河猴参与一种操作性条件反射范式的过程中，同时记录了133对中央前回神经元，该范式要求两个神经元中的一个在30至60毫秒的峰间间隔（ISI）范围内持续放电。在每5分钟的行为期结束时，计算两个神经元放电率波动之间的相关性。这些相关性被用作神经元之间同步性的指标。对于大多数神经元对，强化所依赖的神经元可以独立于同时记录的神经元的活动进行控制。在75%的实验中，与休息期相比，操作期内神经元之间的同步性降低。只有5%的实验中，神经元对在操作期内与休息期相比持续表现出同步性增加。如果猴子在休息期出现脑电图困倦迹象，神经元之间的同步性会变得更强。
