Tsuru H, Iwata M, Shigei T
Experientia. 1983 Jun 15;39(6):577-8. doi: 10.1007/BF01971104.
Isolated rabbit veins preconstricted by either norepinephrine, methoxamine or potassium were relaxed by histamine in the presence of mepyramine, a histamine H1-antagonist. The relaxation was not antagonized by atropine, propranolol and indomethacin but by an H2-antagonist cimetidine. It is likely that histamine relaxes the rabbit veins through H2-receptors.
预先用去甲肾上腺素、甲氧明或钾使兔离体静脉收缩，在组胺H1拮抗剂美吡拉敏存在的情况下，组胺可使其舒张。这种舒张作用不受阿托品、普萘洛尔和吲哚美辛的拮抗，但受H2拮抗剂西咪替丁的拮抗。组胺很可能通过H2受体使兔静脉舒张。
