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欧洲獾(Meles meles L.)延迟着床期间的血浆雄激素模式。

Plasma androgen patterns during delayed implantation in the European badger (Meles meles L.).

作者信息

Mondain-Monval M, Bonnin M, Scholler R, Canivenc R

出版信息

Gen Comp Endocrinol. 1983 Apr;50(1):67-74. doi: 10.1016/0016-6480(83)90242-3.

DOI:10.1016/0016-6480(83)90242-3
PMID:6852523
Abstract

Androstenedione and testosterone were measured by radioimmunoassay after chromatography on celite microcolumns throughout the delayed implantation period in the European badger (Meles meles L.). Androstenedione and testosterone concentrations varied from 0.05 to 22 ng/ml, and from 30 pg/ml to 359 pg/ml, respectively. There was a typical biphasic pattern in the fluctuation of these two steroids. Androstenedione levels increased between June and August (X= 7.9 +/- 0.8 ng/ml), decreased from September to November (X = 2.3 +/- 0.3 ng/ml), and then increased again from December to February (X = 6.1 +/- 0.7 ng/ml). The same fluctuations of the testosterone levels were observed throughout the diapause, but the concentrations were lower. The overall correlation between androstenedione and testosterone was highly significant (r = 0.75, P less than 0.001). There was also a similarity between the androgen and progesterone patterns of secretion (r = 0.31), particularly at the end of the delay period (r = 0.73, P less than 0.001). No correlation could be demonstrated between androgens and estrogens.

摘要

在欧洲獾(Meles meles L.)整个延迟着床期内,通过在硅藻土微柱上进行色谱分离后,采用放射免疫分析法测定雄烯二酮和睾酮的含量。雄烯二酮和睾酮的浓度分别在0.05至22纳克/毫升和30皮克/毫升至359皮克/毫升之间变化。这两种类固醇的波动呈现出典型的双相模式。雄烯二酮水平在6月至8月间升高(X = 7.9 ± 0.8纳克/毫升),9月至11月间下降(X = 2.3 ± 0.3纳克/毫升),然后在12月至2月间再次升高(X = 6.1 ± 0.7纳克/毫升)。在整个滞育期观察到睾酮水平有相同的波动,但浓度较低。雄烯二酮和睾酮之间的总体相关性非常显著(r = 0.75,P < 0.001)。雄激素和孕酮的分泌模式之间也存在相似性(r = 0.31),尤其是在延迟期结束时(r = 0.73,P < 0.001)。未发现雄激素与雌激素之间存在相关性。

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