欧洲獾（Meles meles L.）延迟着床期间的C21甾体和皮质素转运蛋白样蛋白

C21 steroids and transcortin-type protein during delayed implantation in the European badger Meles meles L.

作者信息

Bonnin M, Martin B, Charron G, Audy M C, Canivenc R

出版信息

J Steroid Biochem. 1984 Feb;20(2):575-80. doi: 10.1016/0022-4731(84)90126-2.

Abstract

A high-affinity corticosteroid-binding protein (CBG) roughly resembling a transcortin-type protein is present in badger plasma. Plasma CBG, corticosteroid and progesterone (P) concentrations were measured in relation to delayed implantation, true progestation and gestation. Two significant CBG increases were observed during pregnancy. The first, in the second half of embryonic diapause coincides with an increase in plasma corticosteroid concentration and the second, during true progestation and gestation, with an increase in P concentration. Relationship of CBG increases with pregnancy in badger are discussed.

摘要

獾的血浆中存在一种高亲和力的皮质类固醇结合蛋白（CBG），其大致类似于皮质素运载蛋白类型的蛋白质。测定了血浆CBG、皮质类固醇和孕酮（P）的浓度与延迟着床、真孕和妊娠的关系。在怀孕期间观察到CBG有两次显著升高。第一次，在胚胎滞育后半期，与血浆皮质类固醇浓度升高同时出现；第二次，在真孕和妊娠期间，与P浓度升高同时出现。本文讨论了獾体内CBG升高与妊娠的关系。