Addis B J, Fox H
Histopathology. 1983 Mar;7(2):287-98. doi: 10.1111/j.1365-2559.1983.tb02242.x.
A case of primary papillary mesothelioma of the ovary is reported and its microscopic and ultrastructural features described. This tumour was an incidental surgical finding and was accompanied by multiple, partially cystic, peritoneal lesions with similar microscopic features. The histological pattern was predominantly papillary with well-differentiated mesothelial cells and a prominent stromal infiltrate that included large numbers of lymphocytes and lipid-filled macrophages. A comparison is made with adenomatoid tumours and with other tumours of ovarian epithelium and it is suggested that this tumour may represent the benign counterpart of one form of clear cell carcinoma of the ovary. The presence of multiple peritoneal lesions may indicate limited malignant potential comparable to some other papillary epithelial neoplasms of the ovary.
本文报告了一例卵巢原发性乳头状间皮瘤,并描述了其显微镜和超微结构特征。该肿瘤是手术中偶然发现的,伴有多个具有相似显微镜特征的部分囊性腹膜病变。组织学模式主要为乳头状,间皮细胞分化良好,间质浸润明显,包括大量淋巴细胞和充满脂质的巨噬细胞。将其与腺瘤样肿瘤及其他卵巢上皮肿瘤进行了比较,提示该肿瘤可能代表卵巢透明细胞癌一种形式的良性对应物。多个腹膜病变的存在可能表明其恶性潜能有限,与卵巢其他一些乳头状上皮性肿瘤相当。