Morgenstern C, Zabel A, Lamprecht J
HNO. 1983 Apr;31(4):140-3.
The symptomatology of Ménièr's disease is delineated by means of 739 cases observed in a period of 25 years. The dilation of the endolymphatic space accompanied by a temporary mixture of endolymph and perilymph substantiates the idea of a nosologic entity as well as the interpretation of the symptoms: vertigo, fluctuating hearing loss, tinnitus, and fullness of the ear. The medical treatment by infusions of Rheomacrodex, vasodilatory substances, antivertiginosa, and psychosedatives is unsatisfying just as surgical treatment by saccotomy, sacculotomy, labyrinthectomy, and other operations at the inner ear. Local application of gentamycin into the middle ear can produce good results; in cases of failure the neurectomy should be taken in consideration. The neurectomy eliminates vertigo, but there remains the need of central compensation and the possibility of appearance of Ménière's disease on the other ear.
通过对25年间观察到的739例梅尼埃病病例的研究，阐述了该病的症状学。内淋巴间隙扩张伴有内淋巴和外淋巴的暂时混合，证实了这一疾病实体的概念以及对症状的解释：眩晕、波动性听力损失、耳鸣和耳部胀满感。通过输注低分子右旋糖酐、血管扩张剂、抗眩晕药和精神镇静剂进行药物治疗效果不佳，同样，通过内淋巴囊切开术、球囊切开术、迷路切除术和其他内耳手术进行手术治疗也不理想。将庆大霉素局部应用于中耳可产生良好效果；若治疗失败，则应考虑进行神经切除术。神经切除术可消除眩晕，但仍需要中枢代偿，且另一侧耳朵仍有可能出现梅尼埃病。
