Sullivan J J, Iwaoka W T
J Assoc Off Anal Chem. 1983 Mar;66(2):297-303.
A high pressure liquid chromatographic procedure is described for assay of toxins associated with paralytic shellfish poisoning (PSP). The method is applicable to saxitoxin, neosaxitoxin, gonyautoxins I through IV, and their sulfocarbamoyl derivatives. Toxins are separated on a bonded phase cyano column and detected by fluorescence following alkaline oxidation (NH+4 and periodic acid). The utility of the HPLC procedure for research and monitoring is discussed.
本文描述了一种用于分析与麻痹性贝类中毒（PSP）相关毒素的高压液相色谱法。该方法适用于石房蛤毒素、新石房蛤毒素、膝沟藻毒素I至IV及其磺基氨基甲酰衍生物。毒素在键合相氰基柱上分离，并在碱性氧化（NH⁺₄和高碘酸）后通过荧光检测。讨论了高效液相色谱法在研究和监测中的实用性。
