Kaffarnik H, Braun B, Eltze C, Hausmann L, Mühlfellner G, Mühlfellner O, Neitzert A, Schneider J, Schubotz R, Zehner J
Z Kardiol. 1978 Jul;67(7):481-6.
The coronary reserve was measured in 119 patients with different types of primary hyperlipoproteinemia. Cardiovascular diseased with clinical manifestation were excluded. 90 patients of same age with normal serum lipids served as controls. The groups did not differ in other risk factors as blood pressure or overweight (the latter excluded in hyperlipoproteinemia type IV). The controls showed decreased coronary reserve in 8%, type IIa patients in 36%, IIb patients in 18% and type IV patients in 23%. The frequency of restriction in coronary flow increased with age: in hyperlipoproteinemic patients of 50 years and more it was found in nearly 40%. Further interesting results were the significantly higher systolic and diastolic blood pressures reached during exercise in our hyperlipoproteinemic patients.
对119例不同类型原发性高脂血症患者进行了冠状动脉储备功能测定。排除有临床表现的心血管疾病患者。选取90例年龄相仿、血脂正常的患者作为对照。两组在其他危险因素如血压或超重方面无差异(IV型高脂血症患者排除超重因素)。对照组冠状动脉储备功能降低者占8%,IIa型患者占36%,IIb型患者占18%,IV型患者占23%。冠状动脉血流受限的发生率随年龄增加:50岁及以上的高脂血症患者中近40%出现该情况。另一个有趣的结果是,我们的高脂血症患者在运动期间达到的收缩压和舒张压显著更高。