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基于数学模型的风疹流行病学特征分析(根据莫斯科10年观察数据)

Analysis of epidemiological peculiarities of rubella based on a mathematical model (according to observations over 10 years in Moscow).

作者信息

Kantorovich R A, Gol'dfarb L G, Volodina N I, Myskin A A

出版信息

J Hyg Epidemiol Microbiol Immunol. 1983;27(1):43-50.

PMID:6854012
Abstract

The main epidemiological values characterizing rubella in Moscow were calculated on the basis of a new mathematical model. Quantitative estimates of the intensity of infection in different age groups of the population were obtained. It has been established that the risk of infection in children is especially high in comparison with adult population. That is why 98% of the population aged 15 are immune. The probability of falling ill with rubella was determined for persons with different antibody levels. The cases of congenital rubella in Moscow are rare due to the low risk of infection in adults and to their immunity acquired in childhood. Consequently, there is no necessity for vaccination against rubella in Moscow at the present time, but it should be recommended to organize constant epidemiological surveillance of congenital rubella.

摘要

基于一种新的数学模型计算了莫斯科风疹的主要流行病学数值。得出了不同年龄组人群感染强度的定量估计。已确定儿童感染风险与成年人群相比特别高。这就是为什么15岁人群中有98%具有免疫力。确定了不同抗体水平人群患风疹的概率。由于成年人感染风险低且在儿童期获得了免疫力,莫斯科先天性风疹病例很少。因此,目前莫斯科没有必要接种风疹疫苗,但应建议对先天性风疹进行持续的流行病学监测。

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