Durisić S, Milosević V, Vuković B, Seguljev Z, Stefanović S
Pokrajinski zavod za zdravstvenu zastitu, Medicinski fakultet, Novi Sad.
Med Pregl. 1993;46(9-10):319-22.
In first phase of a study on congenital Rubella syndrome incidence in Vojvodina population, we examined serologic status of 1225 non-pregnant and 846 pregnant women of generative age, as well as the level of exposure to the Rubella virus. On the basis of antihemagglutinin antibody titre 93.2% of women were found to have antibody titre level above or equal to 1/8. There were no significant differences between the proportions of seropositive women in different age groups (x2 = 1.20; P = 0.88). The percentage of seropositive women varied from 82 to 97% (x2 = 29.85; P = 0.005), according to the year of the investigation. The lowest percentage was registered (1980). Rubella virus susceptibility index was 13.1%. On the basis of proven seroconversion the examination of even Rubella serum samples showed the morbidity rate of 7.18%. The level of exposure of pregnant women to the Rubella virus was 71.0%, during all the period of pregnancy. In such circumstances total Rubella morbidity of pregnant women was 2.13%; the highest level, 21%, was in persons form 18 to 19 years of age. It was not possible to make an analysis of pregnancy outcomes and the consequences in pregnant women.
在一项关于伏伊伏丁那人群先天性风疹综合征发病率的研究的第一阶段,我们检查了1225名非孕妇和846名育龄孕妇的血清学状况,以及风疹病毒的暴露水平。根据抗血凝素抗体滴度,发现93.2%的女性抗体滴度水平高于或等于1/8。不同年龄组血清阳性女性的比例之间没有显著差异(x2 = 1.20;P = 0.88)。根据调查年份,血清阳性女性的百分比从82%到97%不等(x2 = 29.85;P = 0.005)。最低百分比记录于1980年。风疹病毒易感性指数为13.1%。根据证实的血清转化情况,对风疹血清样本的检测显示发病率为7.18%。在整个孕期,孕妇风疹病毒暴露水平为71.0%。在这种情况下,孕妇风疹总发病率为2.13%;最高水平为21%,出现在18至19岁的人群中。无法对妊娠结局及对孕妇的影响进行分析。