Dixon R M, Lieberman L M, Gould H R, Hafez G R
J Nucl Med. 1983 Jun;24(6):505-7.
A rare functional black adenoma (FBA) of the adrenal cortex was found to be the cause of hypertension and cushingold features in a 34-yr-old white female. Preoperative studies included [131I]iodocholesterol scanning (ICS) of the adrenal glands, which demonstrated the increased release of cortisol from the affected adrenal gland, with the failure of the opposite adrenal gland to record. This is evidence that cortisol was suppressing adrenocorticotropin (ACTH) output by the pituitary gland. This case documents the clinical utility of "functional" imaging techniques in this clinical setting.
一名34岁的白人女性被发现患有罕见的肾上腺皮质功能性黑色腺瘤（FBA），这是其高血压和库欣样特征的病因。术前检查包括肾上腺[131I]碘胆固醇扫描（ICS），结果显示患侧肾上腺皮质醇释放增加，对侧肾上腺无摄取。这证明皮质醇抑制了垂体分泌促肾上腺皮质激素（ACTH）。该病例证明了“功能性”成像技术在这种临床情况下的临床应用价值。
