Austin S G, Schnatter A R
J Occup Med. 1983 Apr;25(4):313-20.
The relationship between chemical exposures and deaths attributable to primary brain tumors among employees of a Texas petrochemical plant was investigated. Cases consisted of 21 deaths in which the underlying cause was confirmed as a primary brain tumor. Two control groups of 80 employees each were randomly selected from 450 decedents known to the company in June, 1979. Potential exposures while employed were compared between cases and controls for five known or suspect carcinogens. Exposure potentials were also compared for an additional 37 chemicals to which at least four cases were potentially exposed. Overall and 15-year latency analyses were performed. The proportion of cases exposed to the five potentially carcinogenic chemicals (including vinyl chloride) were lower than or consistent with the proportion of exposed controls. No statistically significant differences between the proportions of cases and controls exposed to the 37 other chemicals were found.
对得克萨斯州一家石化厂员工接触化学物质与原发性脑肿瘤所致死亡之间的关系进行了调查。病例包括21例死亡，其根本死因经确认为原发性脑肿瘤。1979年6月，从该公司已知的450名死者中随机挑选了两个对照组，每组80名员工。对病例组和对照组在工作期间接触5种已知或疑似致癌物的潜在情况进行了比较。还对至少4例病例可能接触的另外37种化学物质的接触可能性进行了比较。进行了总体分析和15年潜伏期分析。接触5种潜在致癌化学物质（包括氯乙烯）的病例比例低于或与接触对照组的比例一致。在接触其他37种化学物质的病例组和对照组比例之间未发现统计学上的显著差异。
