Bredael J J, Vugrin D, Whitmore W F
J Urol. 1983 May;129(5):985-8. doi: 10.1016/s0022-5347(17)52500-8.
We treated 208 patients with newly diagnosed nonseminomatous germ cell tumors of the testis between January 1975 and March 1978. Patients with stages I and II disease underwent retroperitoneal lymph node dissection, and the majority of patients with stage II neoplasm received adjuvant chemotherapy afterwards. Patients with stage III and palpable stage II neoplasm had initial chemotherapy with or without subsequent surgery. The over-all cure rates were 96 per cent (76 of 79) for patients with stage A, 94 per cent (31 of 33) with stage IIA, 83 per cent (35 of 42) with stage IIB and 35 per cent (15 of 43) with stage III disease. The stage of disease at the time of diagnosis, local extent of the primary tumor, nodal category in stages I and II cancer, and chemotherapy were factors influencing relapse rate and over-all survival.
1975年1月至1978年3月期间，我们对208例新诊断的睾丸非精原细胞瘤生殖细胞肿瘤患者进行了治疗。I期和II期疾病的患者接受了腹膜后淋巴结清扫术，大多数II期肿瘤患者随后接受了辅助化疗。III期和可触及的II期肿瘤患者先进行化疗，之后可选择是否进行手术。A期患者的总体治愈率为96%（79例中的76例），IIA期为94%（33例中的31例），IIB期为83%（42例中的35例），III期疾病为35%（43例中的15例）。诊断时的疾病分期、原发肿瘤的局部范围、I期和II期癌症的淋巴结分类以及化疗是影响复发率和总体生存率的因素。
