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[抗生素在妇科感染中的临床评估]

[Clinical evaluation of antibiotics in gynecologic infections].

作者信息

Chimura T

出版信息

Jpn J Antibiot. 1983 Feb;36(2):241-8.

PMID:6854937
Abstract

The clinical effects of antibiotics (lincomycin, cefotaxime, ceftizoxime, piperacillin, fosfomycin, cefmenoxime, cefotetan, cefbuperazone, cefpiramide and ceftazidime) were evaluated in gynecologic infections. 1. A total of 161 patients with gynecologic infections was treated with each antibiotic and an overall response rate was 150/161 (93.2%). The efficacy rate was 72/78 (92.3%) in intrauterine infection, 29/31 (93.5%) in uterine adnexitis, 22/25 (88.0%) in intrapelvic infection and 27/27 (100%) in external genital infection. 2. Each antibiotic proved bacteriologically effective in 94.3% of the patients with simple intrauterine infection, in 84.0% of patients with mixed intrauterine infection, in 100% of 6 patients with uterine adnexitis, in 100% of 11 with intrapelvic infection and in 100% of 25 with external genital infection. There were 160 isolated organisms with clinical effective rate of 93.8%. Eleven (6.8%) of 161 patients had infections caused by anaerobic bacteria and all of them showed clinical response to therapy.

摘要

评估了抗生素(林可霉素、头孢噻肟、头孢唑肟、哌拉西林、磷霉素、头孢甲肟、头孢替坦、头孢哌酮、头孢匹胺和头孢他啶)对妇科感染的临床疗效。1. 共有161例妇科感染患者接受了每种抗生素治疗,总有效率为150/161(93.2%)。子宫内感染的有效率为72/78(92.3%),子宫附件炎为29/31(93.5%),盆腔内感染为22/25(88.0%),外生殖器感染为27/27(100%)。2. 每种抗生素对单纯子宫内感染患者的细菌学有效率为94.3%,对混合性子宫内感染患者为84.0%,对6例子宫附件炎患者为100%,对11例盆腔内感染患者为100%,对25例外生殖器感染患者为100%。共分离出160株病原体,临床有效率为93.8%。161例患者中有11例(6.8%)由厌氧菌引起感染,所有患者对治疗均有临床反应。

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