Maĭ F T, Liakishev A A, Polesskiĭ V A, Sidorenko B A, Gerasimova E N
Kardiologiia. 1983 Mar;23(3):33-7.
The concentration of high density lipoproteins (HDL) and the phospholipid content of HDL2 and HDL3 were estimated in the plasma of 23 women with coronary heart disease (CHD) and in the control group of 38 healthy women. The concentration of HDL cholesterol (HDL-C) was significantly reduced in patients with CHD in comparison with the control group. There was also a significant decrease of the per cent content of lecithin and an increased content of sphingomyelin, especially in HDL2 subfraction. It is concluded that the reduction of HDL-C content is accompanied by changes in the phospholipid content of HDL that may result in reduction of cholesterol-acceptor properties of these particles.
对23名冠心病（CHD）女性患者的血浆以及38名健康女性组成的对照组的血浆进行了高密度脂蛋白（HDL）浓度以及HDL2和HDL3的磷脂含量测定。与对照组相比，冠心病患者的HDL胆固醇（HDL-C）浓度显著降低。卵磷脂的百分比含量也显著降低，而鞘磷脂含量增加，尤其是在HDL2亚组分中。结论是，HDL-C含量的降低伴随着HDL磷脂含量的变化，这可能导致这些颗粒的胆固醇接受特性降低。
