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[脂质代谢紊乱对缺血性心脏病患者血液流变学特性的影响]

[Effect of disorders of lipid metabolism on the rheological properties of blood in patients with ischemic heart disease].

作者信息

Dudaev V A, Parfenov A S, Torkhovskaia T I, Khalilov E M, Ivanov A S

出版信息

Kardiologiia. 1983 Mar;23(3):37-42.

PMID:6855059
Abstract

A comparative study of the effects of changes in erythrocytic membrane and serum lipid metabolism on rheologic blood properties (total blood and plasma viscosity, erythrocyte aggregation and deformability) was conducted in 70 patients with chronic coronary disease. A positive correlation was established between total blood and plasma viscosity and serum triglyceride levels. Increased serum cholesterol levels were not found to affect plasma viscosity in any significant manner. Erythrocyte deformability was reduced in coronary patients with high molar cholesterol/phospholipids ratio in erythrocyte membranes, patients with high serum cholesterol levels showing the highest membrane molar cholesterol/phospholipids ratio.

摘要

对70例慢性冠心病患者进行了红细胞膜和血清脂质代谢变化对血液流变学特性(全血和血浆粘度、红细胞聚集性和变形性)影响的比较研究。全血和血浆粘度与血清甘油三酯水平之间存在正相关。未发现血清胆固醇水平升高对血浆粘度有任何显著影响。红细胞膜中胆固醇/磷脂摩尔比高的冠心病患者红细胞变形性降低,血清胆固醇水平高的患者红细胞膜胆固醇/磷脂摩尔比最高。

相似文献

1
[Effect of disorders of lipid metabolism on the rheological properties of blood in patients with ischemic heart disease].[脂质代谢紊乱对缺血性心脏病患者血液流变学特性的影响]
Kardiologiia. 1983 Mar;23(3):37-42.
2
[Effect of the plasma lipoprotein spectrum on the cholesterol level in erythrocyte membranes].[血浆脂蛋白谱对红细胞膜胆固醇水平的影响]
Vopr Med Khim. 1985 Jul-Aug;31(4):83-7.
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Patol Fiziol Eksp Ter. 2004 Jan-Mar(1):13-5.
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[Blood viscosity in ischemic heart disease with different types of hyperlipoproteinemia].[不同类型高脂蛋白血症的缺血性心脏病中的血液粘度]
Kardiologiia. 1977 Jun;17(6):79-82.
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[Surgical correction of hyperlipoproteinemia in patients with ischemic heart disease].
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[New approaches to the evaluation of the cholesterol content of plasma lipoprotein fractions in normo- and hyperlipoproteinemias].[正常脂蛋白血症和高脂蛋白血症中血浆脂蛋白组分胆固醇含量评估的新方法]
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