Lorenzi G L, Bertini G, Peveraro A
Minerva Med. 1983 Jun 23;74(26):1569-72.
Thirty patients with articular pain had been treated with proglumetacin during average 12 days. Twenty-three (77%) responded well to very well to the treatment. Total symptom score decreased by 49%, and each tested symptom (painful, inflammatory and functional) significantly improved, in spite of the short observation period. Tolerance was defined good to excellent in 26 patients (87%). Overall, 10 patients complained of mild to moderate accessory symptoms, mainly heartburn and epigastric pain. No C.N.S. symptoms were observed, nor variations of the laboratory tests, carried out in 16 patients. Proglumetacin, therefore, showed to be a suitable drug for the fast and safe management of articular pain of orthopedic interest.
30例关节疼痛患者接受了丙谷美辛治疗，平均疗程为12天。23例（77%）对治疗反应良好至极佳。尽管观察期较短，但总症状评分下降了49%，各项测试症状（疼痛、炎症和功能）均有显著改善。26例患者（87%）的耐受性被评定为良好至极佳。总体而言，10例患者抱怨有轻度至中度的副症状，主要是烧心和上腹部疼痛。16例患者未观察到中枢神经系统症状，实验室检查也无变化。因此，丙谷美辛显示出是一种适用于快速、安全治疗骨科相关关节疼痛的药物。
