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喀麦隆啮齿动物疟原虫(约氏疟原虫、查巴迪疟原虫和文氏疟原虫)的形态学及酶电泳变异观察

Observations on the morphology and electrophoretic variation of enzymes of the rodent malaria parasites of Cameroon, Plasmodium yoelii, P. chabaudi and P. vinckei.

作者信息

Lainson F A

出版信息

Parasitology. 1983 Apr;86 (Pt 2):221-9. doi: 10.1017/s0031182000050393.

Abstract

Six samples of rodent blood infected with malaria parasites were isolated from Cameroon. Of these, 2 contained mixed infections of Plasmodium vinckei and P. yoelii, 3 contained P. vinckei alone and 1 P. chabaudi alone. Each isolate was cloned and the resulting lines examined for morphology of blood and mosquito forms, and for electrophoretic variation in enzymes. The P. chabaudi and P. yoelii lines were morphologically and enzymically identical to isolates of the Central African Republic. Similarly, 1 P. vinckei line was identical to an isolate of the Central African Republic. The remaining 4 P. vinckei lines showed considerable variation, some enzymes being like those in isolates of surrounding regions, while others were unique to Cameroon.

摘要

从喀麦隆分离出6份感染疟原虫的啮齿动物血液样本。其中,2份含有文氏疟原虫和约氏疟原虫的混合感染,3份仅含有文氏疟原虫,1份仅含有查巴迪疟原虫。对每个分离株进行克隆,并对所得品系进行血液和蚊媒形态以及酶的电泳变异检查。查巴迪疟原虫和约氏疟原虫品系在形态和酶方面与中非共和国的分离株相同。同样,1个文氏疟原虫品系与中非共和国的1个分离株相同。其余4个文氏疟原虫品系表现出相当大的变异,一些酶与周边地区分离株中的酶相似,而另一些酶则是喀麦隆独有的。

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