Efimov A S, Gulyĭ M F, Shcherbak A V, Dzvonkevich N D
Probl Endokrinol (Mosk). 1983 Mar-Apr;29(2):10-4.
The blood oxaloacetate, alpha-ketoglutarate, malate and citrate concentrations and citrate excretion with the urine were studied in 86 patients with diabetes mellitus. An enhanced citrate content and lowered oxaloacetate, malate and alpha-ketoglutarate concentration were detected in the blood of patients with diabetes mellitus. Compensation of the disease and combined pathogenetic therapy are factors, promoting normalization of Krebs cycle metabolite content.
对86例糖尿病患者的血液草酰乙酸、α-酮戊二酸、苹果酸和柠檬酸浓度以及尿中柠檬酸排泄情况进行了研究。在糖尿病患者血液中检测到柠檬酸含量增加，而草酰乙酸、苹果酸和α-酮戊二酸浓度降低。疾病的代偿和联合病因治疗是促使三羧酸循环代谢物含量恢复正常的因素。
